Manu Tuilagi has called time on his international career with England and will move to French club Bayonne later this year.
Manu Tuilagi, George Martin and Luke Cowan-Dickie are part of the reinforcements England have called up for their clash with Scotland.
Owen Farrell steered England into the semi-finals of the World Cup after Steve Borthwick's side faced down a Fiji fightback in a dramatic 30-24 victory in Marseille.