By SABC Sport
15th April 2023
Tsitsipas was bidding for a third title in a row at the event but American Fritz produced an excellent performance to win 6-2 6-4.
Tsitsipas has been struggling with a shoulder problem since reaching his second grand slam final at the Australian Open, and he told reporters: "It's probably the worst injury that I had on the tennis court so far.
"I have tried to change a few things to help my arm, because it's the most important thing for me in the next 15 years. I'm trying my best to keep it as healthy as possible."
In the semi-finals, Fritz will take on Russian fifth seed Andrey Rublev, who was a 6-1 7-6 (5) winner over German qualifier Jan-Lennard Struff.
Sixth seed Holger Rune got the better of in-form third seed Daniil Medvedev, who was back on court only hours after saving match points in a gruelling victory over Alexander Zverev.
Rune eased to a 6-3 6-4 win, after which Medvedev bit back at Zverev, who had criticised the Russian's sportsmanship in a post-match interview.
"Sascha (Zverev) is living in his own world," said Medvedev. "Sascha, when he loses, we can find maybe 25 interviews of him where he does say some strange things. When he says someone is not playing fair, you're like, OK, great. Look at yourself in the mirror'."
Lorenzo Musetti was unable to follow up his big victory over Novak Djokovic, going down 6-2 6-2 to his fellow young Italian Jannik Sinner, who now takes on Rune.