Harlequins ended their victory drought with a 39-29 win against the Sharks to reach the Champions Cup knockout phase alongside the Durbanites.
The Sharks have made several injury-enforced changes for Saturday's final pool match of the Heineken Champions Cup against Harlequins in London.
Sharks Director of Rugby Neil Powell has named a 28-man touring squad, who will travel tonight to London for their Heineken Champions Cup return leg pool match against Harlequins at The Stoop on Saturday.
Sharks boss Neil Powell was happy with his team's performance in their Champions Cup victory over Harlequins last week but is looking for an improved display against Bordeaux-Begles.
The Sharks nearly paid the price for their ill discipline but ultimately held on to defeat Harlequins 39-31 in pulsating Champions Cup encounter in Durban.
Springbok captain Siya Kolisi will lead a formidable Sharks side when they take to the field for Saturday's opening-round Champions Cup clash with Harlequins at Kings Park.