Caelan Doris shone and Jack Conan suffered an injury scare as Ireland launched their World Cup warm-up fixtures by easing to a 33-17 win over Italy in Dublin.
Junior Springbok head coach Bafana Nhleko named five uncapped players in his starting team to face Italy in Paarl on Thursday.
Ireland prop Finlay Bealham has been ruled out of the remainder of the Guinness Six Nations with a knee injury sustained in Saturday's win over Italy.
Grand Slam-chasing Ireland avoided a major upset to keep themselves on course for Six Nations glory with a disjointed 34-20 bonus-point win over Italy.
England dismantled a disappointing Italy to give the Steve Borthwick era lift off with a 31-14 Guinness Six Nations victory at Twickenham.
Ethan Dumortier scored a try on his France debut as the Les Bleus kick-started their Six Nations title defence with a 29-24 bonus-point victory over Italy at the Stadio Olimpico.