The Englishman, who leads the league with 21 goals, missed training at Sabener Strasse on Thursday, sparking concern among fans and pundits alike.
Eagle-eyed supporters and media spotted Kane's absence as Bayern ramped up preparations for the weekend. The 31-year-old has endured a bruising spell recently, starting with a facial blow during a clash with Bayer Leverkusen's Piero Hincapie last weekend.
That knock left him doubtful for Bayern's midweek Champions League tie against Celtic, where he limped through the first half of the 1-1 draw before Kingsley Coman replaced him at halftime. Now, a fresh twist has emerged: Kane has picked up a minor calf injury, leaving his availability for Matchday 23 in serious doubt.
Bayern boss Vincent Kompany will be sweating over his star man's fitness with third-placed Frankfurt, nicknamed Die Adler, set to roll into the Allianz Arena. "Harry's a warrior, but we'll assess him day by day," Kompany said earlier this week, keeping his cards close to his chest.
The Bavarians have leaned heavily on Kane's razor-sharp finishing this season, and his potential absence could tilt the scales in a fixture that promises fireworks.
On X, Kane offered a brief update late Thursday, saying, "Working hard to get back out there, thanks for the support." Bayern also posted, "Harry's pushing to return, but we're taking no risks," alongside a training clip without their talisman.
With Frankfurt flying high and Kane's fitness hanging in the balance, all eyes are on Munich for what could be a defining weekend in the Bundesliga race.