New signing Terrence Dzvukamanja netted on debut to help SuperSport United to a 2-0 victory against Richards Bay at the Peter Mokaba Stadium.
Mamelodi Sundowns kicked off the defence of their PSL title with a 2-1 victory over Sekhukhune United at the Peter Mokaba Stadium in a game that saw both teams finish with ten men.
The PSL season concludes on Saturday with second place in the standings, the top-eight and the relegation battle going down to the wire.
Orlando Pirates are in a favourable position to secure second place in the league, which would earn them a spot in next season's CAF Champions League.
Maritzburg United gave themselves a chance of avoiding relegation after holding champions Mamelodi Sundowns to a 1-1 draw at Loftus on Tuesday.
Nedbank Cup finalists Orlando Pirates and Sekhukhune United played to a 1-1 draw in their DStv Premiership encounter at the Orlando Stadium on Saturday.