England coach Steve Borthwick has named Jamie George as the captain of his squad that has no space for Kyle Sinckler or Billy Vunipola.
England prop Mako Vunipola has announced he is retiring from international rugby.
Prop Joe Marler has been added to England's growing injury list ahead of the Six Nations.
In the wake of perpetually underfire England captain Owen Farrell taking a break from Test rugby, the powers that be are set to provide more support for players' mental wellbeing.
England will be without flanker Tom Curry for the upcoming Six Nations after Sale revealed he is to undergo hip surgery.
Veteran official Wayne Barnes has called time on his career, retiring as the most experienced international rugby referee of all time.