The Sharks are counting the cost of their defeat to Toulouse in the Investec Champions Cup after a further three Springboks were ruled out of action.
The Sharks host Stade Toulouse at Hollywoodbets Kings Park in a third match of the Investec Champions Cup group stage on Saturday.
Cape Town witnessed a pulsating clash on Saturday as the Stormers triumphed over the Sharks 24-20 at a packed Cape Town Stadium, with over 52,000 spectators in attendance.
In a nail-biting United Rugby Championship clash, the Sharks triumphed over the Bulls with a 20-17 victory at Kings Park on Saturday.
The Sharks continued their good form at Kings Park as they bagged all five points in a 41-24 URC victory over Munster on Saturday.
Springbok captain Siya Kolisi starred on his return for the Sharks as the home team beat defending United Rugby Championship (URC) champions Glasgow 28-24 in Durban.