Toulouse booked their Heineken Champions Cup semi-final spot with a 54-20 victory over the Sharks at Stade Ernest-Wallon.
The Bulls finally ended their winless run with a demolition job over Griquas, while the Sharks edged the Pumas in Friday night's Currie Cup action.
When the Sharks travel to Toulouse for Saturday's Heineken Champions Cup quarterfinal clash with Stade Toulousain at the Stade Ernest Wallon, it will be a venture into the unknown.
Speaking after the match, Sharks Director of Rugby Neil Powell was proud of the way his team stood up and performed against Munster.
The Lions scored four tries during an impressive second half as they claimed a 34-22 bonus-point victory over the Sharks in the Currie Cup.
The big day approaches as the Sharks host Munster in the Heineken Champions Cup Round of 16 knock-outs at Kings Park on Saturday in a historic first for the Durban team.