Newcastle boss Eddie Howe was chuffed to secure his first win against Pep Guardiola, as his charges beat Manchester City in the Carabao Cup.
Alexander Isak fired Newcastle into the Carabao Cup fourth round at the expense of Manchester City.
Newcastle winger Harvey Barnes could be facing months on the sidelines as he awaits a specialist's verdict on the foot injury he suffered at Sheffield United.
Rafael Leao was guilty of an incredible miss which let Newcastle off the hook as their Champions League opener at AC Milan finished goalless.
Liverpool reportedly made a £100million bid for Newcastle United midfielder Bruno Guimaraes, as the transfer window neared its close.
Eddie Howe admits defeat at Brighton is a warning Newcastle cannot allow their Champions League adventure to distract from the "ruthless" Premier League.