Keshav Maharaj bowled a marathon spell of 28 overs and took three wickets to help the Proteas restrict the West Indies to 145-4 at stumps on day three of the first Test.
The Proteas finished day two of the first Test against the West Indies on 344/8 on a slow day in Port of Spain.
Only 15 overs were bowled on a rain-interrupted opening day of the first Test between West Indies and South Africa in Trinidad with the Proteas 45/1 at stumps.
England racked up a thumping 10-wicket victory and a 3-0 series sweep in three days at Edgbaston thanks to the efforts of Mark Wood and Ben Stokes.
Captain Temba Bavuma wants the Proteas to hit the ground running in the Test series against the West Indies next month despite a lack of red-ball cricket recently.
England may have sealed the Test series 2-0, but West Indies captain Kraigg Brathwaite insists his team are playing for pride in Edgbaston this week.