The Lions are in a race to make the top eight of the United Rugby Championship table.
Munster became the first European team to win at Ellis Park in the United Rugby Championship (URC) this season after demolishing the Lions 33-13.
The Lions took full advantage of going up against a weakened Leinster outfit at Ellis Park on Sunday, as they romped to a 44-12 URC victory.
The Lions were eliminated from the Challenge Cup with a 27-17 defeat against Benetton in Treviso on Saturday evening, despite a numerical advantage.
Ospreys kept alive their hopes of an end of season play-off spot with an impressive 36-21 bonus-point win over the Lions in Swansea.
The Lions claimed an impressive 38-14 victory over Connacht at Dexcom Stadium despite losing prop Asenathi Ntlabakanye to an early red card on Saturday.