The Lions handed Cardiff their eighth consecutive United Rugby Championship defeat on Saturday as they pulled off a 34-13 victory in Johannesburg.
The Lions take on Welsh side Cardiff Rugby in a crucial Round 16 match of the United Rugby Championship at Emirates Airline Park on Saturday.
The Lions are in a race to make the top eight of the United Rugby Championship table.
Munster became the first European team to win at Ellis Park in the United Rugby Championship (URC) this season after demolishing the Lions 33-13.
The Lions took full advantage of going up against a weakened Leinster outfit at Ellis Park on Sunday, as they romped to a 44-12 URC victory.
The Lions were eliminated from the Challenge Cup with a 27-17 defeat against Benetton in Treviso on Saturday evening, despite a numerical advantage.