Edinburgh marched into the EPCR Challenge Cup quarter-finals with a commanding 24-12 victory over the Lions in the Round of 16 at the DAM Health Stadium.
The Lions' URC playoff hopes were dealt a blow in Wales on Friday as they suffered a narrow 20-17 defeat against Cardiff in wet and testing conditions.
Lions head coach Ivan van Rooyen has announced his squad to face Cardiff at Arms Park on Friday, featuring several key players back in the lineup.
Loosehead prop Ox Nche makes a welcome return to the Sharks side named to host the Lions in the return leg of the United Rugby Championship derby.
The Lions delivered a commanding performance at Ellis Park to dismantle the Sharks 38-14 in a wet and scrappy South African URC derby.
The Bulls were back to winning ways in the United Rugby Championship (URC) after a strong start saw them beat the Lions 31-19 in the Jukskei derby at Loftus.