Fourth seed Stefanos Tsitsipas was taken the distance before the Greek collected a 7-5 3-6 6-3 win over Argentinian 25th seed Sebastian Baez.
World No 3 Daniil Medvedev and World No 5 Stefanos Tsitsipas both made their debuts in the Madrid Open on Saturday, and safely booked their spots in the third round.
Top seed Carlos Alcaraz and Stefanos Tsitsipas both made it safely through the semi-finals of the Barcelona Open on Friday.
While the likes of Stefanos Tsitsipas and Carlos Alcaraz made it safely through to the quarter-finals of the Barcelona Open on Thursday, others weren't so lucky.
Taylor Fritz brought an end to Stefanos Tsitsipas' winning streak at the Monte-Carlo Masters by defeating the defending champion in the quarter-finals.
World number three Stefanos Tsitsipas is eager to get his favourite part of the season underway: the clay court swing.