After Wales picked up their first Wooden Spoon in the Six Nations since 2003, head coach Warren Gatland offered to resign.
Leading Ireland to Six Nations glory could be Peter O'Mahony's final act on international rugby's stage.
Ireland secured consecutive Six Nations titles with a hard-fought 17-13 victory over Scotland, ending their opponents' Triple Crown hopes.
Wales suffered the ignominy of a first Six Nations wooden spoon since 2003 after Italy posted a 24-21 victory over them in Cardiff.
Ireland have stuck with the starting XV narrowly beaten by England for Saturday's Guinness Six Nations title decider against Scotland in Dublin.
George Ford continues at flyhalf as England keep faith with the side that stunned Ireland for their attempt at winning the Guinness Six Nations title.