The Lions handed Cardiff their eighth consecutive United Rugby Championship defeat on Saturday as they pulled off a 34-13 victory in Johannesburg.
Benetton took advantage of Murray Koster's red card to snatch a 25-24 victory over the Sharks which keeps alive their hopes of a United Rugby Championship (URC) play-off place.
The Bulls overcame a second-half implosion to secure all five points in a 40-34 win over United Rugby Championship leaders Glasgow Warriors at Loftus Versfeld.
The Stormers took a giant step towards sealing a United Rugby Championship play-off spot after producing a flying finish to earn a 44-21 win over battling Dragons at Rodney Parade.
The Sharks are back in action at Kings Park on Saturday when they entertain Italian outfit Benetton in the closing stages of the United Rugby Championship.
The Stormers welcome back three players from injury for their United Rugby Championship encounter with Dragons RFC in Newport on Friday night.