Trent Alexander-Arnold will miss Liverpool's Premier League clash with Southampton due to a hamstring injury, while Virgil van Dijk is ready to play.
While Southampton have struggled for points so far on their return to the Premier League, head coach Russell Martin believes there are still plenty of positives to take from the experience.
Erling Haaland found the net again as Manchester City extended their unbeaten home run in the Premier League to over two years, edging Southampton 1-0 in a tight contest.
Arsenal came back from a goal down to beat Southampton 3-1 thanks to two quickfire goals in the second half from Kai Havertz and Gabriel Martinelli.
Black Stars forward Antoine Semenyo shined for Bournemouth, scoring in their 3-1 Premier League win over Southampton at the Vitality Stadium on Monday night.
Southampton boss Russell Martin praised goalkeeper Alex McCarthy's after he made a penalty shootout save against Everton to send the Saints into the fourth round of the Carabao Cup.