Proteas head coach Shukri Conrad said his bowlers were "bereft of ideas" after conceding a record total of more than 300 against England in the second T20I at Old Trafford on Friday.
Phil Salt led a ruthless England batting display as they thrashed South Africa by 146 runs in the second T20I on Friday — the home side's biggest win in the format and the Proteas' heaviest defeat.
Two South African cricket stalwarts have been added to a worrying Proteas' injury list.
South Africa claimed a 14-run win over England in their opening T20 International at Sophia Gardens, where rain wreaked havoc throughout the evening.
Proteas T20 captain Aiden Markram has credited the SA20 for giving a wide range of players an opportunity to showcase their skills, therefore widening the pool for the national selectors.
The Proteas have suffered a blow after experienced batter David Miller was ruled out of the three-match T20I series against England, starting in Cardiff on Wednesday, with a hamstring strain.