Chelsea's dominant first-half display against Leeds United at Stamford Bridge was overshadowed by concern over Marc Cucurella after the Spaniard was withdrawn at the interval.
Tottenham's relegation fears deepened after a 2-1 home defeat to Newcastle increased the pressure on head coach Thomas Frank and extended the club's alarming slide down the Premier League table.
Benjamin Sesko struck deep into stoppage time to rescue a 1-1 draw for Manchester United against West Ham at the London Stadium on Tuesday.
Arsenal midfielder Mikel Merino has begun his recovery after undergoing surgery on a fractured right foot, leaving the Gunners uncertain over when the Spain international will return.
Jack Grealish has confirmed his season is over after undergoing surgery on a foot stress fracture, bringing a frustrating halt to what had been a promising spell at Everton.
Virgil van Dijk demands a swift response from his Liverpool team-mates after Sunday's damaging 2-1 Premier League defeat to Manchester City at Anfield.