Everton's final season at Goodison Park started with a disheartening 3-0 defeat to Brighton, as new head coach Fabian Hurzeler enjoyed a winning Premier League debut.
Liverpool forwards Diogo Jota and Mohamad Salah spoiled Ipswich's Premier League return and handed new boss Arne Slot a debut victory.
Leicester's preparations for the new season have been hit with news Patson Daka will be ruled out for a "few months".
Joshua Zirkzee came off the bench to score on his debut and earn Manchester United a late victory in Friday's Premier League opener against Fulham.
Mikel Arteta has challenged Arsenal to take another step forward this season and has sensed the same determination in his players.
Rodri looks set to miss Manchester City's Premier League opener against Chelsea on Sunday.