South Africa utility back Damian Willemse says they are expecting a tough Test match against a well-built Italy team in Turin on Saturday.
Springbok lock Lood de Jager has been banned for four Tests after receiving a red card for foul play against France in Paris last weekend.
Springbok assistant coach Tony Brown stressed on Monday that the Boks would not underestimate Italy as the two teams prepare to square off in Turin on Saturday.
Springboks captain Siya Kolisi hailed his team's ability not to panic as they dug in to secure a 32-17 victory over France in Paris, despite being down to 14 players.
South Africa's impressive win over France in Paris helped them breach the 93-point barrier in the World Rugby rankings and increase their lead over second-placed New Zealand.
Springboks head coach Rassie Erasmus revealed Siya Kolisi had no complaints when he was subbed off for Ruan Nortje after Lood de Jager was shown a red card.